Metathione and Glutathione

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Published: 18th November 2010
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When I first heard about Metathione, also called Met Tathione, I didn't think that supplements were in regular use that would lighten the skin. Being from a beach city, I'm used to people wanting a tan, not the other way around. So I did a little bit of research into metathione, mostly to find out if it was safe and beneficial to the skin and the main reasons people use it. I found out some surprising results. Not only is Metathione used to reduce skin pigmentation, it also has very powerful range of health benefits. Metathione has glutathione as its active ingredient. Glutathione is technically a protein, being made of 3 amino acids, cysteine, glutamic acid, and glycine, which are produced normally by the body and have a very strong antioxidant effect. But more about that later.

Metathione has Glutathione in it, so they are very similar in nature, though depending on what you're using it for, metathione might be more effective. Metathione comes in different forms including soaps, lotions, and pill supplements, and works by actually lightening the skins pigments and returning a lighter rosier complexion, which is thought to be more youthful and beautiful for certain skin complexions. The active ingredient is L-Glutathione, and has a few other compounds such as Alpha Lipoic Acid, L-Cysteine, and Vitamin C as well. So you see that metathione is basically just an enhanced version of glutathione.

Here are a few of the reported benefits of Metathione, or Met Tathione:

Reduces Aging

Reduces Dark Patches

Reduces Skin Spots and Blemishes

Returns a Skin's Natural Glow

High in Antioxidants

Aids Against Degenerative Disorders like Alzheimers and Parkinsons

Immune System Booster

Metathione has actually been used to treat some blood disorders and as a cleansing agent, supporting the liver and detoxifying it of heavy metals and other toxins. It has also been used by doctors to reduce the damage and symptoms of radiation exposure and chemotherapy for cancer. Metathione is powerful in the body because it helps to shield cells from a specific kind of harmful oxidization. Dermatologists also prescribe metathione along with Vitamin C to reduce skin pigmentation. The average duration of use is 3-6 months in order to see effects.

Metathione, as we've already discussed, has glutathione as it's main and active ingredient. So why is ALA the second ingredient? The reason is something you might not think. Glutathione has shown in clinical trials to not be very bio-available, which means that the digestive system can't absorb a whole lot of it into the blood stream through supplementation. That being said however, other components, such as Alpha Lipoic Acid, stimulate glutathione production in the body. That's why they're in there. Instead of finding a metathione supplement or product, you should check out a straight glutathione supplement that has extra compounds in it like ALA and Milk Thistle, which will work together with the glutathione to raise the levels in the body.

It's interesting, but pigmentation loss and skin whitening is actually technically one of the side effects of glutathione and metathione. Even though a lot of people, generally in countries like the Philippines and Japan, use glutathione supplements to bring a slight lightening to the complexion of the skin, that effect is actually listed as one of the side effects. It's not a harmful side effect, mind you, but not the main effect that the body uses glutathione for. The body uses glutathione primarily as an antioxidant within the cell and as a detoxifying agent.


Metathione is mostly just an enhanced glutathione supplement that's made specifically for skin whitening. For more in the realm of glutathione products, check out another of my articles about cosmetic glutathione soap.

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